RESUMO
In this paper we conducted an experimental study to evaluate the impact of soiling on the temperature and electricity production of two photovoltaic technologies (Poly-Si and CdTe) under a hot semi-arid climate of Morocco. For this purpose, two modules -from each technology-were exposed for one year where one is cleaned every day and the other is left to accumulate soiling on its surface. In parallel, the electrical parameters, the weather data and the modules temperature were monitored using high precision instruments. Results show that the Poly-Si technology is highly affected by soiling in comparison to the CdTe where the measured daily Soiling ratio (SR) can reach 0.70 and 0.73 respectively. This values lead to a drop on the energy production of 15% for the Poly-Si and 13%. Regarding the modules temperature (Tm) results show that soiling has an impact on increasing the temperature for both technologies, but the Poly-Si module is more affected than the CdTe one, where the daily average temperature difference between the clean and the soiled modules is around 1.5 °C and 1.3 °C for both technologies, respectively.
RESUMO
Melanoma is the most aggressive of skin cancer derived from genetic mutations in the melanocytes. Current therapeutic approaches include surgical resection, chemotherapy, photodynamic therapy, immunotherapy, biochemotherapy, and targeted therapy. However, the efficiency of these strategies may be decreased due to the development of diverse resistance mechanisms. Here, it has been proven that therapeutic monoclonal antibodies (mAbs) can improve the efficiency of melanoma therapies and also, cancer vaccines are another approach for the treatment of melanoma that has already improved clinical outcomes in these patients. The use of antibodies and gene vaccines provides a new perspective in melanoma treatment. Since the tumor microenvironment is another important factor for cancer progression and metastasis, in recent times, a mechanism has been identified to provide an opportunity for melanoma cells to communicate with remote cells. This mechanism is involved by a novel molecular structure, named extracellular vesicles (EVs). Depending on the functional status of origin cells, exosomes contain various cargos and different compositions. In this review, we presented recent progress of exosome applications in the treatment of melanoma. Different aspects of exosome therapy and ongoing efforts in this field will be discussed too.
